Evaluation Of Liver Biochemical Parameters In Manganese Miners

2021-08-29T17:08:56+00:00

Evaluation of Liver Biochemical Parameters in

Background: Manganese (Mn) related jobs may cause manganism especially in miners Side effects include neural and pathological disorders In spite of liver is the main organ that filters Mn (99%) but few studies has performed about Mn toxicity in liver so no specific biochemical indicator is available (Gunnar) Razavian H, Mohammad S, Rabiee M Evaluation of liver biochemical parameters in manganese miners Zahedan J Res Med Sci 2014; 16(6) : 64 7 8 PejovicMilic A, Chettle DR, McNeill FE Quantification of manganese in human hand bones: a feasibility study Phys Med Biol 2008; 53(15) : 4081 92 9 Finley BL, Santamaria ABEffects of Manganese Exposure on Blood Iron Indices study the effect of zinc and iron salts fortification of the feed on biochemical, Histopathological and cytogenetic parameters in rats Results individually or a in combination at concentrations of 20 and 40 mg/kg/bw ferrous chloride and Zinc acetate at a daily dose for 8 weeks, caused remarkable increase in the activity of liver enzymesBiochemical, Histopathological and Cytogenetic

Evaluation of manganese superoxide dismutase and

biochemical parameters in mesothelioma patients Keywords: Asbestosis, mesothelioma, mitochondrial oxidative, manganese superoxide dismutase, thioredoxin2 Introduction Asbestos is a wellknown human carcinogenic mineral [1] It is a fibrous silicate and used for optimal material for various construction and covering purposesBiochemical evaluation of hydroxyurea derivative schiff bases in liver of rats In this study, it was aimed to examine the antioxidant and antihepatotoxic effects of hydroxyurea derivative Schiff bases on serum biochemical parameters (AST, ALT, LDH, urea, creatinine and total bilirubin) and antioxidant parameters (SOD, CAT, GPx, MDA)Biochemical evaluation of hydroxyurea derivative The variation in the biochemical parameters in PI and PIR, in the summer and winter, shows that metals caused toxic effects and seasonal variation, even at low concentrations The liver is the organ responsible for detoxification and excretion and, therefore, is the target of Ecotoxicological evaluation of water from the

Evaluation of manganese superoxide dismutase and

Asbestos is a mineral known as human carcinogenic material Exposure to asbestos both in an occupational and environmental way causes asbestosis and mesothelioma ROS contributes to the development of pulmonarytoxicity induced asbestosWe aimed to determine the levels of important mitochondrial substances such as manganese superoxide dismutase (MnSOD) and Thioredoxin Concentrations of blood parameters and their interrelationships were investigated in dairy cows, during their lactation period, to determine the variations among parameters and the most reliable indices which could be useful for milk yield improvement Blood was taken monthly during the 300 days of lactation and divided into early, mid, and late lactationMonthly evaluation of blood hematological, Methods: A 25year, open label, crossover study, was designed to determine the effect of UDCA (1520 mg/kg per day for 12 months, off for 6 months, and on again for 12 months) on clinical symptoms, biochemical test results, galactose and caffeine elimination halflives (t½), and quantitative hepatic scintigraphy in 13 subjects aged 131 ± 21 years (10 of whom completed the entire study Effect of Ursodeoxycholic Acid Therapy on Hepatic

Sex differences in subacute manganese intoxication

Protective role of quercetin against manganeseinduced injury in the liver, kidney, and lung; and hematological parameters in acute and subchronic rat models Drug Des Dev Ther , 11 ( 2017 ) , pp 2605 2619 , 102147/DDDTSEvaluation of liver biochemical parameters in manganese miners SM Razavian, M Rabie Zahedan J Res Med Sci (ZJRMS) 16 (6), 6467, 2014 2: 2014: Effect of Dietary Sunflower oil on Growth Performance of Broiler chicks Kept at Two Cage Densities During Summer Season‪Mahmoud Hassan Rabie‬ ‪Google Scholar‬ There were no treatmentrelated changes in haematological, serum biochemical parameters or histopathological lesions Some changes observed in organ weights were considered by the authors as not “toxicologically relevant” In blood and all tissues tested, including liver, kidney, spleen, lung and brain, the concentration of iron showed no Safety and efficacy of iron oxide black, red and yellow

Manganese and its Compounds (CICADS)

Wedler F (1994) Biochemical and nutritional role of manganese: an overview In: KlimisTavantzis DJ, ed Manganese in health and disease Boca Raton, FL, CRC Press, pp 137 Wennberg A, Iregren A, Struwe G, Cizinsky G, Hagman M, Johansson L (1991) Manganese exposure in steel smelters a health hazard to the nervous systemTrace elements (or trace metals) are minerals present in living tissues in small amounts Some of them are known to be nutritionally essential, others may be essential (although the evidence is only suggestive or incomplete), and the remainder are considered to be nonessential Trace elements function primarily as catalysts in enzyme systems; some metallic ions, such as iron and copper Trace Elements Diet and Health NCBI Bookshelf‐ manganese dioxide hydrates containing Ba or K (psilomelane, cryptomelane) In neutral or acidic aqueous solutions manganese (II) exists in the form of [Mn(H 2 O) 6] 2+ ions and is stable to oxidation In alkaline solutions, however, the hydroxide Mn(OH) 2 is formed Manganese(II) ions Manganese and its inorganic compounds [MAK Value

Biomarkers of Trace Mineral Intake and Status The

Manganese Plasma manganese concentrations reflect dietary manganese intake Levels are decreased on a manganeserestricted diet and have been found to be higher in women who consume 15 mg Mn/d compared with those of women who consume 17 mg Mn/d There is no adequately confirmed evidence that manganese deficiency is either of clinical or A large liver bank consisting of 226 biopsy specimens of similar histopathologic condition was probed for total CYP content (nmol CYP/gram liver), and antipyrine clearance was measured in vivo in the same subjects (Sotaniemi et al 1997) Antipyrine is a nonspecific CYP substrate and thus is a general index of hepatic CYP functionPharmacokinetic and Pharmacodynamic Factors That The expanding applications of nanotechnology seem to be a response to many technological, environmental, and medical challenges The unique properties of nanoparticles allow for developing new technologies and therapies Among many investigated compounds is manganese and its oxides, which in the form of nanoparticles, could be a promising alternative for gadoliniumbased contrast agents used Nanomaterials Free FullText Applications and

Homeostatic and toxic mechanisms regulating

PAPAVASILIOU PS, MILLER ST, COTZIAS, GC (1966) Role of liver in regulating distribution and excretion of manganese Am J Physiol 211: 211216 [ Links ] PASCAL LE, TESSIER DM (2004) Cytotoxicity of chromium and manganese to lung epithelial cells in vitroManganese Plasma manganese concentrations reflect dietary manganese intake Levels are decreased on a manganeserestricted diet and have been found to be higher in women who consume 15 mg Mn/d compared with those of women who consume 17 mg Mn/d There is no adequately confirmed evidence that manganese deficiency is either of clinical or Biomarkers of Trace Mineral Intake and Status The ‐ manganese dioxide hydrates containing Ba or K (psilomelane, cryptomelane) In neutral or acidic aqueous solutions manganese (II) exists in the form of [Mn(H 2 O) 6] 2+ ions and is stable to oxidation In alkaline solutions, however, the hydroxide Mn(OH) 2 is formed Manganese(II) ions Manganese and its inorganic compounds [MAK Value

Homeostatic and toxic mechanisms regulating

PAPAVASILIOU PS, MILLER ST, COTZIAS, GC (1966) Role of liver in regulating distribution and excretion of manganese Am J Physiol 211: 211216 [ Links ] PASCAL LE, TESSIER DM (2004) Cytotoxicity of chromium and manganese to lung epithelial cells in vitroThe neurobiochemical disturbances observed concurrently with clinical and subclinical The water is treated by chlorination and sodium silicate to control the microbiologic parameters and remove particulates Statistical analyses Longterm followup of workplace and well water manganese effects on iron status indexes in manganese minersHair Manganese and Hyperactive Behaviors: Pilot Wedler F (1994) Biochemical and nutritional role of manganese: an overview In: KlimisTavantzis DJ, ed Manganese in health and disease Boca Raton, FL, CRC Press, pp 137 Wennberg A, Iregren A, Struwe G, Cizinsky G, Hagman M, Johansson L (1991) Manganese exposure in steel smelters a health hazard to the nervous systemManganese and its Compounds (CICADS)

Appendix 9 Manganese (Inorganic Salts) Spacecraft

In miners suffering from manganese intoxication, the halflife of manganese is 34 d, whereas healthy miners had a fast turnover of only 15 d Also, in mice, Britton and Cotzias (1966) reported a twocompartmental wholebody clearance of manganese, as reported in humans TABLE 12 EFFECT OF DIETARY MANGANESE ON THE MINERAL COMPOSITION OF LIVER, KIDNEY, AND MUSCLE IN CHICKSEXP 2a Treatment Mineral concentration (ppm, dry matter basis) Added Mn, ppmb Calcium Phosphorus Magnesium Manganese Zinc Iron Copper Liver 0 39629 9, 71621 113 53 79337 29223fg 166 6Bioavailability and toxicity of manganese in ruminants Metalbased octane boosting gasoline additives such as methyl cyclopentadienyl manganese tricarbonyl (MMT) and Ferrocene (dicyclopentadienyl iron) have been used for many years Their usage, especially in modern gasoline vehicles equipped with advanced emissions control systems, has been controversial Concerns have been raised that combustion products from MMT and Ferrocene Impact Assessment of MetalBased Octane Boosters:

Manganese Tissue Dosimetry in Rats and Monkeys:

Manganese (Mn), a common element in the environment, naturally occurs in air, soil, and water Mn is used in the production of steel and other alloys, which accounts for > 90% of its global demand (US Geological Survey, 2008)Other industrial uses of Mn include welding and metal working, battery production, glass and ceramics manufacturing, and the octaneenhancing gasoline additive Exposed manganese miners in several countries have suffered from "manganese madness," characterized by hallucinations, emotional instability and numerous neurological problems Longterm manganese toxicity produces muscle rigidity and a shuffling gait similar to that seen in patients with Parkinson’s disease (Politis et al, 1980)Environmental Health Criteria 223 INCHEM2

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